Psilocybin vs. SSRI, Is it a Win?

Gentle critique of the hot new science: It's the big study we been waiting for, SSRIs vs psychedelic-assisted therapy.


The results? A tie. But is that the whole story?

Science is good at measuring 1 thing at a time, bad at seeing the bigger picture and bad at replicating real-world situations. With enough trials and researchers, eventually science sees a bigger picture, but it takes a while.


So that's why I like to mention the limitations of a study rather than just the headline. Research headlines are really misleading, they are extremely circumstantial conclusions but we are so used to generalizing them the way we do with other news..


The main one here is that it was a 6-week study, just enough time to get over the SSRI effectiveness hump where the side effects start to wain and the symptom-suppressive effects kick in. But one can imagine the journey of "long-standing, moderate-to-severe major depressive disorder" is not well understo